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1985, 02, 11-12+74
血清高密度脂蛋白胆固醇测定对原发性肝癌的诊断价值
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摘要:

本文测定172例各种肝病的血清高密度脂蛋白胆固醇(HDLC)和总胆固醇(TC),并与99例正常人对照。发现各肝病组血清HDLC和HDLC/TC比值降低,尤以原发性肝癌组降低最显著,不仅远低于正常人,而且明显地低于其他肝病组。初步认为,凡肝病患者的血清HDLC低于40mg/dl或HDLC/TC比值低于0.28,应警惕肝内新生物存在。

Abstract:

To establish the diagnostic significance in hepatocellular carcinoma, serum high-densitylipoprotein cholesterol(HDL-C)and total cholesterol(TC)were determined in a total of172 cases of liver diseases and 99 healthy controls. HDL-C and HDL-C/TC ratio decreasedin various liver diseases as compared with those in controls. Patients with hepatocellularcarcinoma had the most markedly decreased HDL-C. There was obvious difference inHDL-C concentrations or HDL-C/TC ratio between hepatic neoplasm and other liverdiseases. Present data showed that less than 40 mg/dl of serum HDL-C or less than 0.28of HDL-C/TC ratio in a patient with liver disease could signal to the physician thepossibility of hepatic neoplasm.

参考文献

1. Devenyi P, et al. Am J Med 1981; 71: 598.

2. Kanel GC, et al. Hepatology 1983; 3(3) : 343.

3. 杨昌国:中华医学检验杂志 1979;2(2) :85。

4. Lewis B. The Hyperlipidaemias. Oxford: Blackwell Sci Pub, 1976: 34.

5. 宫田康司,他:肝脏 1983;24(2) :167。

6. 孟宪镛等:中华消化杂志 1981;1(4) :264。

7. 牧濑淳子,他:临床病理 1978;26(3) :240。

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引用信息:

[1]徐克成,叶林,孟宪镛,等.血清高密度脂蛋白胆固醇测定对原发性肝癌的诊断价值[J].南通大学学报(医学版),1985(02):11-12+74.

发布时间:

1985-03-15

出版时间:

1985-03-15

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