南通大学学报(医学版)

参考文献

[1] SANGER H L, KLOTZ G, RIESNER D, et al. Viroids are single-stranded covalently closed circular RNA molecules existing as highly base-paired rod-like structures[J]. PNAS,1976, 73(11):3852-3856.

[2] HANSEN T B, JENSEN T I, CLAUSEN B H, et al. Natural RNA circles function as efficient microRNA sponges[J]. Nature, 2013, 495(7441):384-388.

[3] RYBAK-WOLF A, STOTTMEISTER C, GLA?AR P, et al.Circular RNAs in the mammalian brain are highly abundant, conserved, and dynamically expressed[J]. Mol Cell,2015, 58(5):870-885.

[4] WESTHOLM J O, MIURA P, OLSON S, et al. Genomewide analysis of Drosophila circular RNAs reveals their structural and sequence properties and age-dependent neural accumulation[J]. Cell Rep, 2014, 9(5):1966-1980.

[5] YOU X T, VLATKOVIC I, BABIC A, et al. Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity[J]. Nat Neurosci, 2015, 18(4):603-610.

[6] CHEN L L. The biogenesis and emerging roles of circular RNAs[J]. Nat Rev Mol Cell Biol, 2016, 17(4):205-211.

[7] GREENE J, BAIRD A M, BRADY L, et al. Circular RNAs:biogenesis, function and role in human diseases[J]. Front Mol Biosci, 2017, 4:38.

[8] ASHWAL-FLUSS R, MEYER M, PAMUDURTI N R, et al.CircRNA biogenesis competes with pre-mRNA splicing[J].Mol Cell, 2014, 56(1):55-66.

[9] LI Z Y, HUANG C, BAO C, et al. Exon-intron circular RNAs regulate transcription in the nucleus[J]. Nat Struct Mol Biol, 2015, 22(3):256-264.

[10] MEMCZAK S, PAPAVASILEIOU P, PETERS O, et al.Identification and characterization of circular RNAs as a new class of putative biomarkers in human blood[J]. PLoS One, 2015, 10(10):e0141214.

[11] ZHANG S, ZHU D N, LI H, et al. Characterization of circ RNA-associated-CeRNA networks in a senescenceaccelerated mouse prone 8 brain[J]. Mol Ther, 2017, 25(9):2053-2061.

[12] MEMCZAK S, JENS M, ELEFSINIOTI A, et al. Circular RNAs are a large class of animal RNAs with regulatory potency[J]. Nature, 2013, 495(7441):333-338.

[13] LASDA E, PARKER R. Circular RNAs:diversity of form and function[J]. RNA, 2014, 20(12):1829-1842.

[14] BURD C E, JECK W R, LIU Y, et al. Expression of linear and novel circular forms of an INK4/ARF-associated noncoding RNA correlates with atherosclerosis risk[J]. PLoS Genet, 2010, 6(12):e1001233.

[15] QU S B, YANG X S, LI X L, et al. Circular RNA:a new star of noncoding RNAs[J]. Cancer Lett, 2015, 365(2):141-148.

[16] CHEN C Y, SARNOW P. Initiation of protein synthesis by the eukaryotic translational apparatus on circular RNAs[J].Science, 1995, 268(5209):415-417.

[17] CAINES R, COCHRANE A, KELAINI S, et al. The RNA-binding protein QKI controls alternative splicing in vascular cells, producing an effective model for therapy[J].J Cell Sci, 2019, 132(16):jcs230276.

[18] LI Y S, REN S H, XIA J W, et al. EIF4A3-induced circBNIP3 aggravated hypoxia-induced injury of H9c2 cells by targeting miR-27a-3p/BNIP3[J]. Mol Ther Nucleic Acids,2020, 19:533-545.

[19] LI X, LIU C X, XUE W, et al. Coordinated circRNA biogenesis and function with NF90/NF110 in viral infection[J].Mol Cell, 2017, 67(2):214-227.e7.

[20] FISCHER J W, LEUNG A K L. CircRNAs:a regulator of cellular stress[J]. Crit Rev Biochem Mol Biol, 2017, 52(2):220-233.

[21] LIU C Y, ZHANG C C, YANG J, et al. Screening circular RNA expression patterns following focal cerebral ischemia in mice[J]. Oncotarget, 2017, 8(49):86535-86547.

[22] MEHTA S L, PANDI G, VEMUGANTI R. Circular RNA expression profiles alter significantly in mouse brain after transient focal ischemia[J]. Stroke, 2017, 48(9):2541-2548.

[23] LIN S P, YE S, LONG Y M, et al. Circular RNA expression alterations are involved in OGD/R-induced neuron injury[J]. Biochem Biophys Res Commun, 2016, 471(1):52-56.

[24] YANG L, HAN B, ZHANG Z T, et al. Extracellular vesicle-mediated delivery of circular RNA SCMH1 promotes functional recovery in rodent and nonhuman primate ischemic stroke models[J]. Circulation, 2020, 142(6):556-574.

[25] ZUO L, ZHANG L, ZU J, et al. Circulating circular RNAs as biomarkers for the diagnosis and prediction of outcomes in acute ischemic stroke[J]. Stroke, 2020, 51(1):319-323.

[26] LU D, HO E S, MAI H C, et al. Identification of blood circular RNAs as potential biomarkers for acute ischemic stroke[J]. Front Neurosci, 2020, 14:81.

[27] LI S H, CHEN L, XU C, et al. Expression profile and bioinformatics analysis of circular RNAs in acute ischemic stroke in a South Chinese Han population[J]. Sci Rep, 2020,10(1):10138.

[28] OSTOLAZA A, BLANCO-LUQUIN I, URDáNOZ-CASADO A, et al. Circular RNA expression profile in blood according to ischemic stroke etiology[J]. Cell Biosci, 2020, 10:34.

[29] HAN B, ZHANG Y, ZHANG Y H, et al. Novel insight into circular RNA HECTD1 in astrocyte activation via autophagy by targeting MIR142-TIPARP:implications for cerebral ischemic stroke[J]. Autophagy, 2018, 14(7):1164-1184.

[30] BAI Y, ZHANG Y, HAN B, et al. Circular RNA DLGAP4ameliorates ischemic stroke outcomes by targeting miR-143 to regulate endothelial-mesenchymal transition associated with blood-brain barrier integrity[J]. J Neurosci,2018, 38(1):32-50.

[31] WU F F, HAN B, WU S S, et al. Circular RNA TLK1aggravates neuronal injury and neurological deficits after ischemic stroke via miR-335-3p/TIPARP[J]. J Neurosci,2019, 39(37):7369-7393.

[32] DONG Z F, DENG L N, PENG Q X, et al. CircRNA expression profiles and function prediction in peripheral blood mononuclear cells of patients with acute ischemic stroke[J]. J Cell Physiol, 2020, 235(3):2609-2618.

[33] NI J S, WANG X Y, CHEN S S, et al. microRNA let-7c-5p protects against cerebral ischemia injury via mechanisms involving the inhibition of microglia activation[J].Brain Behav Immun, 2015, 49:75-85.

[34] SUN H X, ZHONG D, WANG C, et al. miR-298 exacerbates ischemia/reperfusion injury following ischemic stroke by targeting Act1[J]. Cell Physiol Biochem, 2018, 48(2):528-539.

[35] BAZAN H A, HATFIELD S A, BRUG A, et al. Carotid plaque rupture is accompanied by an increase in the ratio of serum circR-284 to miR-221 levels[J]. Circ Cardiovasc Genet, 2017, 10(4):e001720.